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More significantly, the maximum interchange probability is high, which is 0.46 for H5N1 NS1 protein(Figure 3D).
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It ensures correctness in calculating interchange probability.
Protein evolution ensures such stability through low interchange probability.
We evaluated the interchange probability for each 15-residue polypeptide of human PrP.
Segments with a high interchange probability are predicted to be switch regions.
As shown in Figure 1C, a peak for the interchange probability occurs in the window with central site 195.
Interchange probability is a numerical measure of the incidence of a disease in terms of knowledge of protein evolution.
After two approaches to remove redundant data, segments used to calculate the interchange probability were quite different from the query segment.
Moreover, as it approximately characterizes the incidence of a disease regarding evolution, interchange probability can surely be used to identify proteins related to CD.
To characterize all genes assigned into one of the nine categories, we apply three assignment rules: maximum probability, maximum probability over 0.6 and maximum probability over 0.7.
The phosphorylation probability is determined based on a pre-defined maximum phosphorylation probability, kphr.
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