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Exact(10)
The maximum inhibitory activity against C. albicans remarkably belonged to the ACN extract of the respiratory tree (p < 0.05) (Fig. 7).
The maximum inhibitory activity against C. glabrata belonged to the PBS extract of the respiratory tree and followed by the ACN extract of the body wall (p < 0.05).
An earlier study in The Gambia similarly found that inhibitory antibodies tended to be lower among adults than children [42], and recent studies by Dent et al. in western Kenya report maximum inhibitory activity among young children, which subsequently declines with increasing age [43].
Various amounts of the leaf protein extracts were titrated against HGP to determine maximum inhibitory activity.
Among the six samples, 3e shows maximum inhibitory activity of 60.25% at higher concentration (400 μg/mL).
It was observed that these combinations had maximum inhibitory activity in 90% clinical isolates at MIC of 15.6 μg/ml.
Similar(50)
The corresponding maximum inhibitory activities of the ME and SFI at the same concentrations were 32%and20%0% respectively.
The maximum inhibitory activities of deacetyl vinblastine (12) and catharanthinic acid (15) are less than 50%; therefore, no IC50 value could be obtained.
The most potent compounds 3- 1- 5-methoxy-1H-benzo[d]imidazol-2-ylthio acetamido -4-methyl benzoic acid (10c, IC50 8.2 μM) and 3- 1- 5-methoxy-1H-benzo[d]imidazol-2-ylthio acetamido -4-methyl(10e, IC50 8.3- 1- 5-methoxy-1H-benzo[d]imidazol-2-ylthio acetamido -4-methyl
Furthermore, the relevance of the C-17 carbonyl group in the D-ring as a structural feature required to achieve maximum aromatase inhibitory activity is also observed for this set of derivatives.
The maximum percentage inhibitory activity of 78.03% was showed at concentration of 500 μg/ml seed extracts followed by bark (78.03%), leaf (69.4%) and fruit pulp (56.9%) at the same concentration.
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