However, maximum induction of apoptosis in SW-13 cells was observed at 48 h, while only high concentrations of BI-2536 resulted in an increase in apoptosis at early time points (Fig. 5c, d).
In present study, the efficiency of corncob xylan in the maximum induction of endo-1,4-β xylanase production was established in 20 g L−1 of concentration, while 25g L−1 of corncob xylan created inhibitory effect on the production of endo-1,4-β xylanase (Fig. 4b).
The maximum induction of ROS in RAW 264.7 cells was, however, lower than that in SH-SY5Y cells (50% increase on control) (25 μg mL-1, 24 h), probably reflecting the relatively higher basal level of intracellular free radicals in macrophages [28].
Maximum induction of a host of proinflammatory cytokines (IL-1α, IL-1β, IL-6, IL-18, IFN-γ, IL-12p40, IL-12p70, TNF-α, MCP-1, VEGF, M-CSF, and GM-CSF) was observed in ApoE+/−-TLR2+/+ mice maintained on a high fat diet and challenged with P. g.
Maximum induction of nSLO-LA by LPS (100 ng/mL) occurred between 4 and 6 h).
Maximum induction of these genes occurred at 12 hpi and was followed by relatively constant expression.
