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Unlike the Ca2+ and SA signaling-related genes, maximum induction in Wangshuibai occurred at 12 hai, suggesting that activation of the JA signaling pathway followed activation of the Ca2+ and SA defense pathways.
Here, genes were ranked based on their maximum induction in response to LPS.
For maximum induction, in vivo, only 4 RNAs are produced on average in 1 hour [ 18].
ALP showed maximum induction in the differentiated control cells at 9 days, with an increase of 167 ± 32% (p ≤ 0.001) relative to undifferentiated control.
Besides maximum induction, in one case we induced using 5% of the concentrations needed for maximum induction (weak induction), and in another with 15% (medium induction).
Comparing to other genes in the heart of hibernating bears, RNA binding motif protein 3 (Rbm3) demonstrated the maximum induction in expression.
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The maximum induction appeared in about 20 min. Conversely, the induction process was much slower under low light illumination (10 µmol photons m−2 s−1).
AtHsp90 genes are induced by various abiotic stresses, such as cold, salt, UV-B, etc., although maximum induction is in response to HS (Figure 3C).
Because the difference of EC50 or EC20 values among PFHxI, PFOI, and PFBDI were small, we compared the estrogenic potency with the maximum induction value in an MVLN assay.
The maximum induction of ROS in RAW 264.7 cells was, however, lower than that in SH-SY5Y cells (50% increase on control) (25 μg mL-1, 24 h), probably reflecting the relatively higher basal level of intracellular free radicals in macrophages [28].
However, maximum induction of apoptosis in SW-13 cells was observed at 48 h, while only high concentrations of BI-2536 resulted in an increase in apoptosis at early time points (Fig. 5c, d).
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