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Moreover, transposed duplications show a decrease of maximum indel lengths from <16 Mya to 16 107 Mya.
We note that in this analysis we computed numbers of indels and maximum indel lengths for parental and transposed duplicates separately.
The correlations between maximum indel lengths and nucleotide substitution rates are generally trivial, perhaps because duplicated genes losing long coding segments are preferentially lost following duplication.
A trend toward shorter exons, more indels and bigger maximum indel lengths suggests that transposed duplications are not perfectly copied and losses of DNA segments frequently happen.
We found that parental loci generally have longer coding-regions and exons, and fewer indels with smaller maximum indel lengths than transposed loci, suggesting that transposed duplications tend to be associated with biased changes in gene structure.
In transposed duplications, parental loci tend to have longer coding-regions and exons, and smaller numbers of indels and maximum indel lengths than transposed loci, reflecting biased structural changes in transposed duplications.
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We impose a maximum indel length of 20 (60) characters for amino acids (nucleotides).
All other INDELible parameters were set to the following: "NUCLEOTIDE 2" model, substitution model: "HKY 2.5," and maximum indel length: 50.
In Arabidopsis thaliana, we denote levels of structural divergence between duplicated genes by differences in coding-region lengths and average exon lengths, and the number of insertions/deletions (indels) and maximum indel length in their protein sequence alignment.
Structural divergence between duplicated genes was measured by differences in coding-region lengths and average exon lengths, and the number of indels and maximum indel length in their protein sequence alignment.
The SPARTA algorithm was run on all biological protein data sets using the following INDELible (Fletcher and Yang 2009) configuration: "AMINOACID2" model, WAG substitution model and "POW" indel size model, maximum indel length: 50.
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