The complete case analysis also gave slightly different results for mean (group difference of 0.6, CI 0.004 to 1.2, p = 0.048, and group difference of 0.7, CI 1.0 to 62.2, p = 0.050) and maximum (group difference of 7.0, CI 1.1 to 15.1, p = 0.091, and group difference of 7.2, CI 1.5 to 15.8, p = 0.104) length of upright events.
Interestingly, the 14-point clinically meaningful difference [ 10] was met by 48% of the placebo patients and over 65% of eluxadoline 100 mg patients and the maximum group difference was observed for a 22 point improvement in which over 25% of placebo patients and over 47% of eluxadoline 100 mg patients responded, respectively, for a group difference of 21.5%.
Relative expression values for all differentially expressed miRNAs by age and/or sex; including maximum age group difference, number of significant age differences, PC1 loading values, and k-means cluster assignments.
When a statistical analysis of the medians was performed in order to minimize the influence of outliers, the maximum between-group difference was 1.98 pg/ml.
It was ensured that the maximum between-group difference in the number of subjects in each medical institution did not exceed two.
No group differences were found for individual maximum power or for the AUC of the two maxima.
Independent t-tests were used to evaluate potential group differences for age, height, weight, and maximum walking time.
ANOVAs showed no group differences on neuropsychological tests of global dementia, cognitive speed/flexibility, verbal and spatial working memory, sustained attention and maximum tapping speed (Table 1).
Quantitative T2 values showed similar group differences.
No other group differences were found.
