Sentence examples for maximum efficacious dose from inspiring English sources

However, this differentiation diminishes at the maximum efficacious dose.

Overall, the efficacy and side effect profiles of the two compounds exhibited differentiation at low to mid doses (0.03 0.1 mg ciclesonide, 0.01 0.03 mg fluticasone), while this differentiation diminished at the maximum efficacious dose (0.3 mg ciclesonide, 0.1 mg fluticasone), likely due to overdosing in this model.

The minimum efficacious dose is 160 mg day−1 (level of evidence: B1).

For this study, a minimum efficacious dose was defined as that dose effecting >25% reduction at study termination (that is, three hours post last dose).

Patients recruited in phase I oncology trials are often treated at doses lower than the maximum tolerated dose (MTD), and therefore may not receive the most efficacious dose available, despite their expectations to the contrary.

Both compounds were devoid of gastric effect at the efficacious dose.

The data show that high in vitro DEI values can be associated with lower efficacious dose.

Such a disconnect makes predicting PK/PD and efficacious dose in humans very difficult.

This combination may only be suitable to test drug candidates for side effect profiles at partially efficacious levels but not the maximum efficacious levels.

Although not powered around any specific hypothesis, this pilot study was designed to identify an efficacious dose while refining inclusion criteria and end points.

Therefore the amount used in the in vivo studies were supramaximal than anticipated efficacious dose levels.