Sentence examples for maximum effective dose from inspiring English sources

Establishing how the dose-effect relationship may vary at different doses and what the maximum effective dose may be is an area for future work.

Given the observed increased side effects of this combination therapy, research should focus on determining the maximum effective dose of sunitinib as well as on deciphering the optimal treatment schedules of the combination therapy.

The focus of phase I studies in these agents is the establishment of the maximum effective dose.

The maximum effective dose of these procedures reached 57 mSv and the unavoidable diagnostic part of the CT-guided intervention produced the lion's share of radiation exposure.

"This kind of study is important for reinforcing the need to give the maximum effective dose," says Alan Lesher, head of the National Institute on Drug Abuse, which funded the study.

The maximum effective dose was 5 mg/kg.

Clearly, the development of these compounds requires important pharmacokinetic and pharmacodynamic (PK/PD) studies to determine important parameters such as the minimal therapeutic dose (MTD), 50% of the maximal effective dose (ED50), the maximum tolerated dose, the lethal dose, and the half life of the drug (t1/2).

It is essential to combine the maximum effective doses of active anticancer drugs in order to obtain a better therapeutic effect.

Cumulatively, these findings suggest that if cells are to be treated as a drug, more is not always better and the minimum and maximum effective doses must be determined based on the clinical application.

The values of mean and maximum effective doses represent approximately 12.5% and 81% of the annual effective radiation dose limit suggested by the International Commission on Radiological Protection.

SiarhEPOELD and CHOrhEPO showed similar half maximum effective doses (ED50 values 0.66 and 0.53 ng/mL, respectively).