Sentence examples for maximum effect achieved from inspiring English sources

The maximum effect achieved soon after dosing, otherwise known as the 'peak' effect, is also of interest for efficacy and safety reasons.

STAT3 knockdown by siRNA was found to be time dependent with the maximum effect achieved at 48 72 hrs of siRNA treatment.

Across all OAD classes, an increase in dose yielded a further decrease in A1C initially with a maximum effect achieved by 3 6 months.

The therapeutic effect of anti-TNF-α in CIA was later shown to relate directly to the stage of CIA development at the time treatment was initiated, with maximum effect achieved when treatment was started just after disease onset.

As shown in the Western immunoblot in the upper panel of Figure 6C, Atiprimod induced procaspase 3 cleavage in a time-dependent manner, with the maximum effect achieved after 4 h.

Our results showed that daily intrathecal injections of ETAR antagonist BQ-123 for 3 consecutive days from day 4 to day 6 after SNL alleviated mechanical allodynia with maximum effect achieved at dose of 30  μg in SNL neuropathic pain model.

Simulations from the model (50 400 mg every other week) illustrated the range and sustainability of response (ACR20: 56 68%, ACR50: 27 42%, ACR70: 11–22% at week 24) with maximum clinical effect achieved at the recommended maintenance dose of 200 mg every other week.

The effects of glycyl-glutamine dipeptide relied in a dose-dependent manner, and the maximum effect was achieved at 20-30 mmoL−1−1 glycyl-glutamine dipeptide.

The maximum effect is achieved between the lowest costal margin and the iliac crest (i.e., at waist level).

Treatment of cells for different periods of time with prazosin revealed that the maximum effect was achieved after 14 16 h incubation (results not shown).

The extent of PKC down-regulation and drug sensitization depended on the duration of TPA exposure; maximum effect was achieved with a 48 h pretreatment.