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The maximum drug encapsulation was 91.50%.
The process and formulation variables were optimized by achieving maximum drug encapsulation efficiency.
In the case of the CEH-loaded zinc pectinate gelispheres, it was determined via constrained optimization that a maximum drug encapsulation efficiency of 28.63% could be obtained under the conditions of 0% (w/v) CEH, 13 h of crosslinking and drying temperature of 60 °C.
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Drug encapsulation tendency increased with addition of MWNT; maximum entrapment was noticed at 1 wt% MWNT level, while at higher MWNT level, the interaction level falls especially at high temperature.
The percent drug encapsulation was determined by separating the free drug from the encapsulated drug using Nanosep centrifugation devices.
Their drug encapsulation efficiency was 72.6%.
Drug encapsulation and loading efficiency were then calculated using Eqs.
The drug encapsulation efficiency was high.
The drug encapsulation efficiency and drug loading were 98.5 % and 14%%, respectively.
However, these formulations showed relatively low drug encapsulation efficiency and drug loading.
maximum drug concentration time.
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