Sentence examples for maximum drug dose from inspiring English sources

Medication doses are given as the maximum drug dose during the first 24 hours.

The pancreas from normal control, diabetic control, and maximum drug dose treated animals were blotted free of mucus.

Where multiple electrocardiograms for a given patient were within this time window, we selected the one corresponding to the maximum drug dose in order to enrich sampling of the high end of the dose range.

The maximum tolerated drug doses are usually 57 75% of the LD50 dose in mice [ 18].

This method of analysis precludes the process of "exception reporting," whereby general practitioners are permitted to omit certain patients from their performance data on the grounds of unsuitability (for example, patients who are already receiving the maximum tolerated hypotensive drug dose, who fail to attend the surgery in spite of three invitations, or who are terminally ill).

High resistance and recurrence rates, together with elevated drug clearance, compel the use of maximum-tolerated drug doses in cancer therapy, resulting in high-grade toxicities and limited clinical applicability.

In all of these studies, maximum drug plasma concentrations increased with drug dose levels [ 5, 16].

14 A linear, dose-dependent relationship was observed in maximum drug concentration levels (Cmax).

maximum drug concentration time.

Subsequently, a second FSC-based optimization was performed with the above-selected compounds, i.e., axitinib (3), erlotinib (4), RAPTA-C (8) and BEZ-235 (9), each now considered at five drug doses with a maximum activity of 25%% at the highest dose (Fig.  2a; single-drug effects in Supplementary Fig. S3).

Any change was based on patient hematological and/or non-hematological parameters on the intended day of treatment as well as the maximum drug-induced toxicity grade observed between dosing.