It is a standard drug delivery method (with maximum concentration of drug in macula), which is used for treatment of chronic uveitis of posterior segment [ 13].
In obese cancer patients, it is believed that fixed drug dosing or dose "capping" (i.e., limiting the body surface area to a pre-specified maximum number) may result in inadequate drug delivery [ 22].
To overcome these limitations, advanced drug delivery systems (DDS) aim at maximum therapeutics efficiency, enhanced bioavailability, targeted drug release, extended drug release profile, minimum toxicity, and reduced dosage frequency to encourage patient compliance.
The desorption kinetics of both carbons presented an initial fast stage, reach the maximum ibuprofen delivery in 300 min and the maximum drug concentration level remained constant up to 24 h.
The 5-FU-loaded cubosomes were evaluated for their in vitro and in vivo characteristics in an attempt to explore their potential as a targeted drug delivery system that could provide a maximum concentration of 5-FU in the liver tissues.
A pulsed US protocol designed to maximum cavitation activity may therefore be a viable method for enhancing drug delivery to the eye.
The synthesized AuNPs have insignificant toxicity at a maximum dose of 100 μM; thus, the particles could be very effective as a drug delivery tool and for other biomedical applications.
Pulmonary drug delivery is the focus of much research and development because of its great potential to produce maximum therapeutic benefit.
Precise drug delivery should be achieved not only at cell level, but also at organelle level to achieve maximum therapeutic responses as well as avoiding possible toxic side effects of the drugs.
Recent development of drug delivery vehicles has opened up the possibility of targeted drug delivery systems with the potential of achieving maximum efficacy with minimal toxicity.
