Sentence examples for maximum drug concentrations from inspiring English sources

However, this drug has some pharmacokinetic limitations including unfavorable maximum drug concentrations (Cmax) and short half lives following systemic bolus injection.

Instead, oral F-DTX and oral NP formulation showed lower maximum drug concentrations that are in the therapeutic window (456 ng/mL and 341 ng/mL, resp).

As predicted by the age- and weight-based models of maximum drug concentrations, children treated with DP had higher recrudescence and reinfection rates than adults did due to PPQ levels insufficient for cure and prophylaxis.

The delay to effect can arise because the site of action is not readily accessible to a drug, which may result in maximum effects occurring later than maximum drug concentrations.

maximum drug concentration time.

The desorption kinetics of both carbons presented an initial fast stage, reach the maximum ibuprofen delivery in 300 min and the maximum drug concentration level remained constant up to 24 h.

The following PK parameters were calculated: area under the curve (AUC), mean residence time (MRT), total body clearance (CLtot), steady-state volume of distribution (V ss), elimination rate constant (K el), biological half-life (T 1/2), maximum drug concentration time (T max), and maximum blood concentration (C max) using standard procedures.

The maximum drug concentration (Cmax) and time to maximum drug concentration (Tmax) were taken directly from the observed data.

Similar trends were observed for minimum (trough) drug concentration (Ctrough) and maximum drug concentration (Cmax).

14 A linear, dose-dependent relationship was observed in maximum drug concentration levels (Cmax).

Maximum drug concentration was rapidly achieved (30 min) when given i.p.