Sentence examples for maximum dose that from inspiring English sources
And researchers in the US are running a small clinical trial investigating whether sodium bicarbonate capsules can help to reduce cancer pain and to find the maximum dose that can be tolerated, rather than testing whether it has any effect on tumours.
Stecksén-Blicks et al. used a maximum dose that was lower than ours (3.4 g/day) [23].
The maximum dose that could be given was 36 mg m−2.
The concentration of the inhibitor was determined as the maximum dose that did not influence proliferation (Fig. S6).
Nevertheless, the maximum dose that can be delivered by single-unit minitablets will always be limited by their small size.
Second, we sought to identify the maximum dose that allowed both CI systems to function within their specification ranges.
Daily oral HU was titrated to maximum doses that did not cause unacceptable marrow depression over an average 2.4 years after randomization.
Doses will be increased by 0.25 mg/day or 0.5 mg/day increments each week to maximum doses that vary by patient weight (<50 kg or ≥50 kg), based on the investigator's assessment of efficacy and tolerability/safety.
ICRP 62 [20] recommended that the maximum radiation dose that causes a 'minor to intermediate' increase of risk levels while preserving social benefit levels that are 'intermediate to moderate' has an effective limit of 10 mSv/year [20, 21].
Further radiation exposure in lungs is not recommended within the first 6 months after SIRT, and in cases where the second SIRT is performed within 6 to 12 months of initial treatment, the recommended dose is < 50% of the maximum tolerated dose that was administered during the initial procedure [10, 11].
In preliminary experiments we evaluated recombinant human IL-18 at doses from 1 to 100 µg/mouse/day for anti-tumor effects in xenografted mice (data not shown), and 15 µg was chosen as a daily dose based on tolerability and efficacy, and because this dose is less than the equivalent maximum tolerated dose that has been established in monkeys and humans [25], [32].
