Sentence examples for maximum cumulative dose from inspiring English sources

The maximum cumulative dose over the first 24 h should not exceed 600 mg.

The test continued until the FEV1 had fallen 15% or the maximum cumulative dose of 635 mg had been administered.

Maximum cumulative dose of doxorubicin was capped at 550 mg m−2, whereas NGR-hTNF was continued until progression, unacceptable toxicity, or patient request.

Epirubicin was continued until progressive disease (PD) was noted or until a maximum cumulative dose of 1000 mg/m had been administered.

The maximum cumulative dose in studies without additional adverse effects reported was daily doses of 100 mg continued over 90 days (Dowell et al. 2004).

According to the study protocol, six patients discontinued doxorubicin when they reached the maximum cumulative dose (i.e., 550 mg m−2).

Subsequently, individual dosing with dosing intervals of 2 to 4 weeks and a maximum cumulative total dose of 600 mg during a 4-week period was allowed [ 8].

BHR was defined as a 20% reduction in FEV1 (PD20) after methacholine challenge, with a maximum cumulative methacholine dose of 2 mg [ 20].

The maximum safe accumulated dose calculated using such an individualized method may be higher in a considerable number of patients and thereby this approach may also increase the maximum cumulative radiation dose to the tumour.

Because of the lengthy duration required for subjects receiving the higher doses, we enroll each subject on the best estimate of the maximum tolerated cumulative dose (MTCD) as soon as each subject is eligible.

If the degree of BM involvement remains in the 20% to 50% range, re-treatment will involve a similar dose of Zevalin; if it is <20%, patients will receive Zevalin to the maximum allowed cumulative dose of 0.4 mCi/kg (or 0.3 mCi/kg for mild thrombocytopenia).