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There was no effect of CPS on the basal, minimum or maximum core body temperature of offspring in 12L:12D or during constant darkness.
The highest value of these measurements was presented as maximum core body temperature.
Minimum and maximum core body temperature measurements over the same time period were also assessed.
Maximum core body temperature over the 12 h after the morning dose for each subject was assessed on each measurement day and for each treatment.
However the differences from placebo in mean maximum core body temperature (Table 4) following XEN-D0501 on day 1 were 0.22°C (1 mg twice daily), 0.50°C (2.5 mg twice daily) and 0.74°C (5 mg twice daily).
Differences from placebo in mean maximum core body temperatures were 0.22°C, 0.5°C and 0.74°C following 1 mg, 2.5 mg and 5 mg twice daily XEN-D0501.
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In terms of core body temperature, the maximum body temperature recorded in a long-distance extreme runner who was still conscious was 41ºC/105.8ºF by the time the body core temperature reaches 42.7ºC/109ºF, a runner will collapse.[3] If left untreated, death can be sudden.
We determined the critical thermal maximum and minimum (CTmax, CTmin) temperatures of toads from each population by manipulating the core body temperature of toads until they were unable to right themselves when placed on their backs.
During each trial, standard termination criteria were applied in accordance with the American Society for Testing and Materials guidelines [ 28]: (1) core body temperature reaching 39.0°C; (2) 60 minutes of exercise; (3) heart rate > 90% of maximum; or (4) fatigue or nausea.
Circadian period estimates were based on plasma melatonin, plasma cortisol, and core body temperature data collected during FD and were computed by a nonorthogonal spectral analysis technique with an exact maximum likelihood fitting procedure [13].
When the core body temperature gets dangerously low and the shivering response is maximally stimulated, Dr. Askew said, energy expenditure can be as high as that from work requiring 40 percent to 50 percent of the person's maximum aerobic capacity.
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