Initially, glucose was rapidly converted mainly into ethanol which reached its maximum concentration after 50 h of cultivation.
Pseudomonas fluorescence after 36 h of incubation starts producing biosurfactant and reaches to its maximum concentration after about 56 h (Abouseoud et al. 2007).
Arabinose was the only sugar which reached the maximum concentration after 96 h of hydrolysis.
The mannose reached its maximum concentration after 24 h hydrolysis with no significant differences throughout the proposed biocatalysis step.
However, after an inflammatory stimulus, an increase in blood CRP concentration occurs within 4 6 h, reaching the maximum concentration after approximately 24 h [ 7, 19].
AUC = area under the curve, CatK = Cathepsin K, Cl = clearance, Cmax = maximum concentration after dosing, Cmin = minimum concentration after dosing, IC50 = half maximal inhibitory concentration, LOD = limit of detection, ODN = odanacatib, res = resorption.
The peak plasma concentration (Cmax), or maximum concentration after a dose is given, and the area under the concentration curve (AUC) increased with an increasing dose of EVG; however, the rate of increase was not proportional to the dose.
