Sentence examples for maximum concentrations achieved from inspiring English sources

E7080 was absorbed rapidly with maximum concentrations achieved within 3 h.

The plasma concentrations of CYT997 at steady state (Css, Table 3) were the maximum concentrations achieved during the infusions.

A computer-controlled syringe pump (402 Dilutor Dispenser; Gilson S.A, Villiers-le-Bel, France) allowed the simulation of drug concentrations by infusion of the drug into the central compartment until the maximum concentration achieved in serum (Cmax) was reached.

† Maximum concentration achieved at the beginning of the IPC treatment.

The mean maximum concentration achieved was higher than that on day 1 (134–536 ng ml−1).

The rate of absorption is indicated by the time taken to reach maximum concentration in the blood [ 17], the maximum concentration achieved after a dose of substrate reflects both of these factors.

For other antibiotics (where concentrations achieved with current regimens remain on the steep part of the concentration-effect relationship), it is the maximum concentration achieved (Cmax) or the related area under the plasma concentration-time curve (AUC) that is the best correlate of bacterial killing (Fig. 4).

The maximum concentration achieved in SSSF3 (11.6% v/v) was not optimal and there is room for further improvement by controlling substrate addition rates, initial enzyme concentrations and addition regimes, yeast strains (including high-temperature tolerant yeasts (Shahsavarani et al., 2013), and yeast nutrients.

This represents 1.9-fold improvement over maximum cell concentrations achieved in planar systems, although it is significantly lower than the maximum cell concentrations achieved in xeno-free hPSC cultures performed in microcarrier-based systems (6 × 10 cells/mL) [ 77].

67 The pharmacokinetic and pharmacodynamic profiles of recombinant glucagon have been evaluated following SC and IM administration, with glucagon demonstrating a short half-life (~8 18 minutes), and maximum plasma concentrations achieved a few minutes after SC or IM injection.

Importantly, each drug was used at the maximum peak serum concentrations achieved as reported in the literature following use for standard clinical indications.