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The pharmacokinetic parameters, such as half-life, mean residence time, maximum concentration were determined.
Those not attaining a cough threshold at the maximum concentration were arbitrarily ascribed a C2 or C5 of 1000 mM.
The pharmacokinetic parameters of Cmax (maximum plasma concentration achieved) and Tmax (time taken to achieve the maximum concentration) were determined by visual inspection of the data.
In liquid phase, both background and maximum concentration were fixed to the pre-existing experimental conditions used for the electrophysiology: they corresponded to a range spanning between 50 μM and 530 μM.
Ethanol productivity (the highest ethanol concentration divided by the total time taken to the maximum concentration) were 0.219, 0.236, 0.184 g-1 h-1 and 0.186 for varieties 55, 70, 74 and 120, respectively.
The PK/PD parameters, i.e., %T > MIC, AUC0 12/MIC (AUC, area under the curve) and Cmax/MIC (Cmax, the maximum concentration) were calculated for each tissue cage, from 0 to 12 h after every drug administration.
Similar(53)
In both cases, the optimal time for reducing the maximum concentration was 60 min of irradiation.
The maximum concentration was more than three-times higher than the minimum concentration.
Dimensionless concentration profiles and the maximum concentration are invariant with mixing intensity.
Exhaust gas analyses showed that the concentration of CO was below 1.6%, while the NOx emission was within 550 ppm and the SOx maximum concentration was 30 ppm.
In the US, the maximum concentration was lowered in April, for the first time in 50 years, to 0.7mg fluoride per litre of water (UK schemes aim to deliver 1mg), amid concerns people are getting too much now it is also in products such as toothpaste and mouthwash.
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