The maximum concentrations of first formed addition products decreased with F/P whereas the maximum concentration reached by di- and trisubstituted phenols was independent of this ratio.
Arterial washout of desflurane was more rapid; arterial concentrations fell to 18% of the maximum concentration reached within 4 minutes, and only 8% of the maximum arterial concentration was present in blood 20 minutes later.
The near bottom maximum concentration reached 330 μM.
The mean maximum concentration reached over 54 μg/ml and was almost 3-fold higher than it was before inoculation.
At steady state, overall plasma levels were roughly comparable to the maximum concentration reached after a single injection of EBID.
Our results show that, during endotoxemia, the endogenous adenosine concentration increases in time, with a maximum concentration reached 2 hours after LPS administration.
During the aerobic phase, NO2-N was accumulated during the initial stage of the final aerobic phase with the maximum concentration reaching 1.6 mg/L.
The levels of toluene and xylenes found in this study are higher than the roadside levels reported in other Asian cities. Hourly maximum concentrations reached 258ppb for toluene, 51ppb for m,p-xylenes, 15ppb for o-xylene, 526ppb for NOx, and 10.5ppm for CO.
For the pour-on application (Fig. 8b), the highest levels of free steroids are also measured between 1 and 3 days after the first treatment, however, for this application, the maximum concentrations reached are much lower (maximum of 410 ng/l for 17β-testosterone).
It is of interest to see that after injection (Fig. 7b), the highest levels of free steroids are measured between 1 and 3 days after the first treatment and that the maximum concentrations reached for the 17β-forms are between 1,000 and 2,000 ng/l and for the 17α-forms are much lower, viz. 100 ng/kg.
Clarithromycin, ofloxacin, roxithromycin and erythromycin-H2O were the dominant antibiotics with maximum concentrations reaching up to 6524, 5411, 964 and 957 ng/L, respectively; while the concentrations of tiamulin, sulfamerazine, sulfathiazole, sulfamethazine, sulfamethizole and sulfisoxazole were below 10 ng/L.
