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The optimal prognostic cut-off (maximum combined sensitivity and specificity) related to in-hospital mortality for proADM was 4.86 nmol/l, with a sensitivity of 0.53, specificity of 0.84, positive likelihood ratio of 3.39, negative likelihood ratio of 0.56, positive predictive value of 64.3 and negative predictive value of 77.1.
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This was obtained by considering all possible thresholds (0.001 0.99999) and selecting the threshold that yielded the maximum combined specificity and sensitivity.
In contrast, both the TPPA test and IgM ELISA were sensitive and the combined sensitivity reached 100%.
In the low-grade group, the sensitivity of the three methods combined was above 80%, but in high-grade group, the combined sensitivity was approximately 100%.
As almost anyone Stier's age will recall, SAT scores then came in two parts — verbal and math — with a maximum combined value of 1600.
Tickets would top out at $35,800 per person, the maximum combined donation any individual can make to a presidential candidate and his party in a given year.
These cut-off values were based on the highest combined sensitivity and specificity (highest sum).
The combined sensitivity will deteriorate the feedforward controller performance if care is not taken in design.
When these biomarkers analyzed for combined sensitivity increases but the specificity decreases.
The maximum combined absolute pathloss uncertainties due to sensor errors and shadowing observed in this simulation are approximately 8 dB.
Two recent meta-analyses found a combined sensitivity of 93 98 % and specificity of 97 98 % for the use of ultrasound for confirming endotracheal tube location [15, 16].
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