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However, challenges remain in optimizing DC-based therapy for maximum clinical efficacy within manufacturing processes that permit quality control and scale-up of consistent products.
Nevertheless, future studies should compare long-term effects of both drugs on brain activation after reaching maximum clinical efficacy.
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Chronomodulated 5-FU clinical efficacy is maximum when administered in nocturnal hours with a concentration peak at 4 00 a.m.
In phase I clinical trials, gefitinib was found to be well tolerated, with clinical efficacy observed well below the maximum tolerated dose.
Taken together, these studies suggest that clinical efficacy from anti-CD4 antibodies could be achieved by maintaining maximum CD4 occupancy and down-modulation throughout the dosing period.
Clinical efficacy of antimicrobial mouthrinses.
They have 25 years building spirometry with a real level of clinical efficacy.
However, their clinical efficacy and safety lack systematic evaluation.
Further studies will be needed to verify the clinical efficacy.
In addition to clinical efficacy, device safety was also acceptable.
We showed biological efficacy in all 5 indications, although clinical efficacy was uneven.
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