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Buprenorphine-induced respiratory depression had a maximum (ceiling) effect at doses of >0.1 mg/70 kg (Dahan et al 2005).
The questionnaire demonstrated minimal floor and ceiling effects with no more than 5% of respondents having minimum (floor effect) or maximum (ceiling effect) scores for all scores.
The total sufentanil dose was the same in both groups and was greater than that necessary to obtain full μ-receptor occupation and maximum ceiling effect.
The dose response curve of sufentanil follows the typical sigmoid curve with a maximum ceiling effect between 1.25 and 1.4 ng ml-1 (see [ 8, 9]).
The maximum ceiling effect was observed in 55.7% of the patients in item "How often have you had back pain in the last week?".
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No study patients obtained the minimum PSO-LIFE score (floor effect) and only 3.2% obtained the maximum score (ceiling effect).
None of the participants obtained a total score of 0 on the scale (floor effect), and only 2.3% of subjects obtained the maximum score (ceiling effect).
None of the participants scored 0 on the scale (floor effect), and 1.93% of subjects obtained the maximum score (ceiling effect).
One person who responded to all 24 items scored maximum (0.2% ceiling effect).
The maximum possible score (ceiling effect) was common with the HUI but was not seen with the CHQ summary scores.
ICC, intraclass correlation coefficient; CI, confidence interval Of the 144 participants, 43 amputees had scores of 40 or higher and 33 (23%) had a maximum possible score (ceiling effect).
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