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To improve drug dissolution of poorly soluble drugs, larger amounts of this excipient were required, and the maximum capsule fill weight that could be achieved was slightly reduced at the same time.
Numerical simulations of a CHSD steady-model indicate the existence of a maximum capsule density beyond which a transition from disperse diffusion (when all capsules actively participate in the diffusion process) to concentrate diffusion (when the capsules close to the heated surface shield the capsules placed further away) occurs.
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Table 2 shows that participants randomised to placebo titrated more rapidly up to the maximum dose capsules.
where Dmax, Dmin, and Davg avg are the maximum, minimum, average capsule diameter, respectively, and derived from the measurement software; d offset is the distance between the center of the outer circle and the center of the inner circle, of the capsule-shell.
Due to restrictions on collecting, a maximum of three capsules were collected from the wild, however, in many cases only one or two capsules were available for collecting at each site.
Accelerated development of a deep-space launching vehicle and capsule "could achieve maximum benefit for American tax dollars by drawing on the cutting-edge technology already being developed for the Constellation program," Boeing said.
All 88 cells reside within an extremely sturdy stainless steel capsule to provide maximum protection.
The entire mission took approximately 11 minutes to unfold, with the capsule hitting a maximum speed of 2,236 miles per hour and height of 389,846 feet.
Not only does the current setup require paying Russia at least $70 million for each seat on the Soyuz, it also limits crews to three people the maximum capacity on the Russian capsule.
We defined the capsulotomy break force as the force measured when the capsule ruptures; the maximum extensibility measured how far the capsular opening was stretched beyond the zero point before breaking.
However, as the majority of NKT cells are excluded from the PALS, we imaged the spleen directly through the collagen capsule (to a maximum depth of 70 μm), which allowed us to visualize NKT cells outside the WP.
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