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TCP + AD + PCL scaffolds showed maximum bone formation after 6 weeks, which was significantly higher than TCP + AD scaffolds.
Both histomorphology and histomorphometric analysis revealed maximum bone formation after 6 weeks when TCP + AD scaffolds were coated with PCL.
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Histomorphometric analysis revealed maximum new bone formation in TCP + AD + PCL scaffolds after 6 weeks.
VEGF is expressed by hypertrophic chondrocytes, and its maximum level of expression precedes the maximum level of bone formation.
X-rays of the ankle joints were made, and these plain radiographs were scored for bone degradation, using a semiquantitative scoring system (demineralization [0-2+], andle and midfoot erosions [0-2+], calcanerosionsion [0-1+], heterotopic bone formation [0-1+]; maximum possible score = 6) according to Boyle and colleagues [ 24].
These GBR characteristics are required to provide the maximum membrane function and mechanical support to the tissue during bone formation.
Bone formation was reduced while resorption was increased, with maximum effects observed within 6 days.
In the responders, bone formation markers bALP and PINP increased to the maximum value on day 42 [ 117].
Maximum bone development ends in one's 20's, after which bone loss gradually begins to exceed bone formation.
In response to the second advancement, new bone formation was significantly higher when compared with single advancement with a maximum increase of 50% and 100% in the condyle and glenoid fossa, respectively.
Alkaline phosphatase as a marker of bone formation was expressed in osteoblast-like cells during long-term cultivation, typically showing a maximum of expression at day 5.
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