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Maximum blood levels of numerous compounds equaled or exceeded 95th-percentile values measured in older children and adults from national surveys, indicating that cumulative exposures for some children may be near the high end of general population exposures.
Median plasma concentration time profiles were similar for all renal function cohorts, with peak concentrations occurring approximately 16 h following patch application, with the exception of the ESRD-hemodialysis cohort, who achieved maximum blood levels 24 h post-application.
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Furthermore, the State of California recently proposed reducing the lead MADL to 0.2 μg/day based on modeling of exposure levels that would result in maximum blood lead levels of 15 μg/dL (Cal/EPA 2015a; Cal/EPA 2015b).
Infusing 2.4 and 4.8 mg/kg/hour in anesthetized and mechanically ventilated pigs over 8 hours resulted in maximum blood sulfide levels of 2.0 and 3.5 μM, respectively (baseline levels 0.5 to 1.2 μM) in our experiments [ 16].
Non-survivors (n = 4) had higher minimum blood glucose levels (217 ± 69 mg/dl vs 128 ± 46, P < 0.005) and higher maximum blood glucose levels (270 ± 120 mg/dl vs 192 ± 61 mg/dl, P < 0.05) compared with the survivors (n = 17).
The observation that women in our population with higher cord blood leads had higher maximum blood pressure levels during labor and delivery is consistent with that work.
Supporting the validity of our blood pressure measures, women with previous hypertension diagnosis during or before pregnancy had higher admission and maximum blood pressure levels, and neither admission nor maximum pressures were correlated with the length of the hospital stay.
The mean maximum blood alcohol levels in alcohol vapor-exposed mice were measured at the end of 20 consecutive days of inhalation and were approximately 1.8 2.0 mg/mL at 08 00 h during the alcohol inhalation period (Fig. 1B).
The usefulness of blood glucose management defined the incidence of hyperglycemia (blood glucose > 180 mg/dL), hypoglycemia (<80 mg/dL), and the maximum glycemic variability (maximum blood glucose level minus minimum blood glucose level).
With regard to blood mercury levels, 64.5% of Cree women exceeded the maximum blood mercury level of 16 nmol/L observed in women from the Quebec City area [ 43], whereas 13.2% exceeded Canada's alert level of 99.7 nmol/L [ 45].
The maximum blood glucose level over each 8-hour period was recorded, as were parenteral daily intake, enteral daily intake and total daily caloric intake.
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