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Furthermore, the State of California recently proposed reducing the lead MADL to 0.2 μg/day based on modeling of exposure levels that would result in maximum blood lead levels of 15 μg/dL (Cal/EPA 2015a; Cal/EPA 2015b).
The peak blood lead concentration from baseline to 7 years of age was the maximum blood lead concentration of any of up to 24 measurements.
The maximum blood lead level of 0.32 μmol/L noted in women from the Quebec City area was exceeded by 26.9% of Cree women [ 43], while 14.2% exceeded Canada's alert level of 0.48 μmol/L [ 44].
Another study examining repeated blood lead levels in children followed from < 1 to 5 years of age detected steeper declines in cognitive abilities in children whose maximum blood lead level never reached 10 μg/dL (Canfield et al. 2003).
The maximum blood lead concentration deemed acceptable for children has declined over the years, from 60 micrograms per deciliter (μg/dL) in 1970 to the present-day level of 10 μg/dL, first established in 1991.
However, increases of this magnitude have been associated with reductions in IQ in young children even when the maximum blood lead concentration observed was < 10 μg/dL (Canfield et al. 2003; Lanphear et al. 2000), and thus are an important public health problem.
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The average maximum (max) blood lead (PbB) of these children during the first 5 years of life was 20.7 micrograms/dL (range 9.2 to 32.5).
According to the U.S. Centers for Disease Control, maximum permissible blood lead level (BLL) is 0.5 μM in children and 1 μM in adults.
An inverse association (p = 0.003) between the child's maximum (peak) blood lead concentration and Full-Scale IQ was apparent down to 2.1 μg/dL, the lowest measured peak concentration in our sample.
The minimum, 5th and 25th percentiles, median, 75th and 95th percentiles, and maximum of blood lead concentrations were 0.53, 1.03, 1.47, 1.81, 2.25, 3.01, and 6.16 μg/dL, respectively.
The maximum value during postpartum the concentration was almost double the minimum blood lead value during late pregnancy in half the subjects; the percentage increase varied from 30 to 95%.
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