Sentence examples for maximum blood concentration from inspiring English sources
maximum blood concentration.
The time to maximum blood concentration is 2 h for oral naratriptan, and 1.5 h for oral sumatriptan [2, 4].
The observed maximum blood concentration (C max) and the half-life time (T 1/2) were obtained by visual inspection of the experimental data.
Extended-release formulations may reduce toxicity with a lower maximum blood concentration (Cmax) and improve efficacy with a higher minimum blood concentration (Cmin).
There were no statistical differences between the novel SR pellets and the recently marketed SR capsule (Advagraf®, Astellas Pharma, Japan) in terms of maximum blood concentration, area under the curve, and half-life values, in both fasted and fed states.
The study measures included Cmax (maximum blood concentration), AUC (area under the blood CyA concentration versus time curve, 0 to 4 hours) and actual time concentrations at individual sampling times.
Pegram et al. (2002) reported maximum blood concentrations of CHBrCl2 ranging from 0.4 to 4 ng/mL due to ingestion versus 39 170 ng/mL due to dermal contact with water containing the same concentration of CHBrCl2.
Pharmacokinetic studies have shown that nicotine mouth spray delivers blood nicotine levels comparable to that of other NRT formulations of the same strength, 5 but that the mouth spray reaches maximum blood concentrations in approximately 10 min, which is significantly faster than the other oral NRT formats.
The CocH3-catalyzed cocaine benzoyl ester hydrolysis to EME was so efficient such that the measured maximum blood cocaine concentration (∼38 ng/ml) was significantly lower than the threshold blood cocaine concentration (∼72 ng/ml) required to produce any measurable physiological effects.
The peak blood lead concentration from baseline to 7 years of age was the maximum blood lead concentration of any of up to 24 measurements.
Total glucose exposure (BG-AUC), maximum blood glucose concentration (BGmax), and maximum glucose excursion from baseline (ΔBGmax) were also significantly lower in pediatric patients administered glulisine compared to RHI (P < 0.05).
