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Given the estimated free concentrations of UCB used in the present study are below its maximum aqueous solubility, it is unlikely that the inhibitory effects of UCB observed in our experimental conditions were mediated by precipitation of UCB aggregates.
Using the corrected affinity constants at pH 7.4, it was estimated that the concentration of free UCB may exceed 70 nM of its maximum aqueous solubility when total serum concentration exceeds approximately 5 mg/dL [50].
The results indicate that rate of dechlorination is a linear function of PCB substrate concentration below the maximum aqueous solubility of PCB 61 and occurs at concentrations as low as 1 ng L 1.
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Voriconazole is a lipophilic drug with a low pH-dependent aqueous solubility (maximum 2.7 mg/mL at pH 1.2).
The maximum uptake for the aromatic compounds decreases with the increase in aqueous solubility of the adsorbates.
Aqueous solubility of solvate-VIII was found to be maximum, however, solvate-I and VIII showed better reduction in total cholesterol and triglyceride levels as compared to atorvastatin against triton-induced dyslipidemia.
The aqueous solubility of the ACV-cocrystal materials was significantly improved with a maximum of malonic acid cocrystal, which was about six times more soluble at 35°C compared with that of parent ACV.
It also showed good aqueous solubility.
The compounds also feature good aqueous solubility.
DQ is economically available, but has the disadvantage of high lipophilicity coupled with exceedingly poor aqueous solubility (0.06 µg/mL).
The azaindoles displayed substantially improved physicochemical properties (lipophilicity; aqueous solubility).
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