Sentence examples for maximum approved doses from inspiring English sources

In a series of comparative studies, azilsartan medoxomil as a single agent was found to be more efficacious than other widely used angiotensin receptor blockers at their maximum approved doses 19,20.

In conclusion, patients with advanced solid malignancies for whom curative therapy was not available tolerated sunitinib and gemcitabine at the maximum approved doses of each agent on Schedule 2/1 with growth factor support.

The study was designed to assess the clinical outcomes, PROs, and safety of 26 weeks of treatment with exenatide QW compared with maximum approved doses of sitagliptin or pioglitazone in patients with type 2 diabetes treated with metformin.

In the first phase, the efficacy and safety of 26 weeks of treatment with exenatide once-weekly were compared with maximum approved doses of sitagliptin or pioglitazone in patients with Type 2 diabetes mellitus treated with metformin [ 3].

29 A randomized, double-blind, double-dummy, multicenter clinical trial was conducted with 514 patients and was designed to assess the clinical outcomes, patient-reported outcomes, and safety of 26 weeks of treatment with exenatide weekly compared with maximum approved doses of sitagliptin or pioglitazone in patients with T2DM.

After 26 weeks of treatment, once-weekly dosing with the glucagon-like peptide 1 (GLP-1) receptor agonist exenatide resulted in superior improvements in glycaemic control and body weight compared with maximum approved doses of the dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin, and the thiazolidinedione, pioglitazone [ 3].

Also, the maximum approved dose (0.5 g/kg/day alanyl-glutamine) to ensure maximal beneficial effect will be given.

Together, these results suggest that high-dose PDE5i could play a role in salvage therapy for multi-drug refractory PAH, realized by taking the PDE5 inhibitors, sildenafil and tadalafil, at the maximum approved dose.

In the four fluoxetine controlled trials and in one citalopram controlled trial, the SSRIs were potentially underdosed compared with reboxetine (according to doses standardised on the basis of the maximum approved dose; see table 2).

In this 52-week trial, subjects were randomized in a 1 1 1 fashion to receive canagliflozin 100 mg, canagliflozin 300 mg, or glimepiride which was titrated to a maximum dose of 6 mg or 8 mg (mean maximum dose was 5.6 mg) based on the maximum approved dose in the study location.

IDegLira is a fixed ratio of insulin degludec (100 U/mL) and liraglutide (3.6 mg/mL) with a maximum dose of 50 Units IDeg/1.8 mg liraglutide, corresponding with the maximum approved dose of liraglutide, where the unit of measure for this fixed-ratio combination will be noted as 'dosing steps'.