The maximum tolerated dose (MTD) of erlotinib (150 mg) is the approved daily dose.
In contrast, the approved daily dose of gefitinib (250 mg) is only one-third of its MTD.
However, according to the European Food Safety Authority EFSAA) [6], the maximum approved rate for OSR is 42 g a.s./ha; hence, the authors only used 30%% of the maximum approved rate.
Maximum production rate (MPR) means the approved maximum daily rate at which oil or gas may be produced from a specified oil-well or gas-well completion.
The rationale for increasing candesartan up to 12 mg daily is that, in Japan, the approved maximum daily dosage of candesartan is 12 mg.
The doses used in the SUCCESS trial tended to favor nsNSAIDs: one half the celecoxib patients received double the dose recommended for OA patients, whereas the 100-mg daily diclofenac dose was less than the maximum dose approved for OA patients in participating countries [ 16, 18, 21, 23, 103].
We focused on 6 data sets including maximum 110 approved and 110 withdrawn drugs for all and nervous system diseases to distinguish approved drugs from withdrawn ones.
Qualifying patients are treated with atorvastatin 40 or 80 mg daily, rosuvastatin 20 or 40 mg daily, or the maximum tolerated and approved dose of one of these agents and fulfill one of the following criteria: LDL-C ≥ 70 mg/dL, non-high-density lipoprotein cholesterol ≥ 100 mg/dL, or apolipoprotein B ≥ 80 mg/dL.
Enter the keywords "maximum temperature daily".
With the data provided by the WMO, we calculated annual mean of daily temperature, daily maximum temperature, daily minimum temperature and daily sunshine hours.
