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We can define a new term, the Relative Efficiency Index (Ei), to simplify things where; <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0007754.e016.PNG" class= inline-graphic"/> Therefore, with Em<(Em)max and thus Ei<1 (see Figure 2B), the global maximum and optimized myelo-architectural design will have a value of Ei = inline-graphic1 = (Em)max/>Em)max).
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Since SE strategy was reported for the first time to successfully isolate lung cancer CTCs in 2009 [30], substantial improvement has been made to render its maximum efficiency and optimized flexibility for enrichment of CTCs, DTCs and CTM in various specimens of different types of cancer patients [31] or tumor mouse models [9], despite how EpCAM is heterogeneously expressed or cell size is varied.
A fixed flux has equivalent minimum and maximum optimized values.
Herein, using a metamodeling based design optimization (MBDO) method, elliptical composite cylinders with VS laminate are designed and optimized for maximum axial buckling capacity.
With the application of PBD, seven independent process variables were investigated and optimized for maximum solubility.
HHO cell was designed, fabricated and optimized for maximum HHO gas productivity per input power.
This paper presents experimental results using a laboratory water chamber, wherein the fundamental parameters of an oscillating water column (OWC) system's geometrical design are individually investigated and optimized for maximum amplification factor of wave energy to mechanically useful energy.
LS and Lzp-PLGA-NPs formulations were effectively radiolabeled with Technetium-99m (99mTc) and optimized for maximum labeling efficiency and stability.
An elutriation device was manufactured and optimized to achieve maximum microplastic recovery.
In the next step, enzymatic hydrolysis process was optimized to recover maximum XOS (Optimized condition: 50 °C, pH 4 and 10 U enzyme dose).
Significant variables affecting the proposed method were evaluated and optimized to achieve the maximum extraction performance.
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