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A non-monotonic relationship between the allele frequency at time T = 20 years and ρ is observed, with a maximum allele frequency observed for ρ = 85%.
In the empirical AFLP data set the maximum allele frequency was set to 0.98.
The minimum allele frequency was set to 0.07 and the maximum allele frequency to 0.92.
For 7 of the 25 SNPs, the maximum allele frequency difference between any 2 populations was > 0.75.
Because SPP detection parameters allowed a maximum allele frequency of 90%, skewed markers were included in the genetic maps.
Maximum allele frequency differences between any 2 populations ranged from 0.10 to 1.0 across SNPs with a mean of 0.65.
Similar(50)
Here, maximum allele frequencies are capped at 0.5 as lag load develops and effective allele number tends to 9.0.
Consistent with neutral evolution, maximum allele frequencies for amino acid variants in PfSERCA were linked closely to cross-genus conservation level.
To facilitate the detection of allele labels that may have been mis-specified by the user, which is critical for the correct determination of the direction of effect, METAL implements an option to output the mean, variance and minimum and maximum allele frequencies for each marker.
The marker with the maximum allele-frequency difference (93.5%) was bPb-8978.
It also permits filtering based on consequence type, minimum and maximum coverage, minimum and maximum variant allele frequency, heterozygosity call, presence in dbSNP, 1000 Genomes Project, the NHLBI exome variant server and 200 Danish exomes, variants present in other samples, and conservation scores (Additional file 1).
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