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However, in genome wide studies, we usually face a situation of large dimensionality and small sample size, and maximizing sample size in the analysis is always desirable.
In order to optimize power by maximizing sample size, we performed a GWAS meta-analysis of eight European samples and one Silk Road population sample (18), having hearing ability measured by pure-tone audiometry and summarized by principal components (PCs).
When estimating the MFHs of the herbivorous dinosaurs, it was important to devise some metric that allowed for the use of both articulated and disarticulated skeletons, thereby maximizing sample size.
We selected this cutoff to balance minimizing the imprecision of defining exposure using home water As level while maximizing sample size, and because few children were expected to have resided in this home since infancy; indeed, only 61 eligible children had resided in this home since their first year of life.
Although there are many ways to deal with missing data [ 19] we have previously shown that this method of dealing with missing or 'not applicable' responses gives similar total scores compared with other approaches such as excluding questionnaires with any missing or 'not applicable' and has the advantage of maximizing sample size [ 9- 12].
Conduct your survey, maximizing sample size and accuracy of responses.
Similar(54)
We openly acknowledge that because our aim was to provide as parsimonious an environmental impact index as possible (maximizing sample sizes and data availability), we could not incorporate all major indices of environmental degradation.
As before, left and right frills (one squamosal plus one half of a parietal) were counted separately, and disarticulated or isolated frill elements were considered to represent a single "frill" in order to maximize sample size.
We analyzed drusen from extra-macular (peripheral) retina from aged normal eyes, as we have done previously [27], [28], [29], in order to maximize sample size for our assays.
We retained all samples to maximize sample size.
Several populations were combined in all analyses to maximize sample size.
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Justyna Jupowicz-Kozak
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