Sentence examples for maximizing efficacy of from inspiring English sources

Successful translation of pluripotent stem cell technology is contingent upon maximizing efficacy of lineage-specification and minimizing risk of dysregulated oncogenic growth.

CAM-ICU: confusion assessment method for the intensive care unit; ICU: intensive care unit; MENDS: maximizing efficacy of targeted sedation and reducing neurological dysfunction; RASS: Richmond Agitation-Sedation Scale.

As reported in the previous issue of Critical Care, Pandharipande and colleagues [ 1] use data from the MENDS (maximizing efficacy of targeted sedation and reducing neurological dysfunction) trial, which compared dexmedetomidine with lorazepam for ICU sedation in a randomized double-blinded fashion [ 7].

In a subgroup of 39 septic patients from the MENDS (maximizing efficacy of targeted sedation and reducing neurological dysfunction) trial, the risk of dying was lower in the group that received dexmedetomidine compared with lorazepam (hazard ratio = 0.3, 95% confidence interval = 0.1 to 0.9, P = 0.036) [ 14].

Patients enrolled in the Maximizing Efficacy of Targeted Sedation and Reducing Neurological Dysfunction (MENDS) trial were assessed daily for delirium using the Confusion Assessment Method-ICU.

The Maximizing Efficacy of Targeted Sedation and Reducing Neurological Dysfunction (MENDS) trial was the first randomized, double-blind trial evaluating the effect of sedative agents on delirium-free and coma-free days [ 35].

We also demonstrate the advantage of reversing the phase encode direction to control the direction of distortion and to maximize efficacy of distortion compensation during data post-processing.

Optimum formulation of adjuvant and vaccine is critical for maximizing efficacy and ease of use.

Targeted biologic therapies have the advantage of maximizing efficacy while often reducing toxicity compared with classical chemotherapeutic agents.

These findings strongly suggest that extended infusion of β-lactams may improve clinical outcome in critically ill patients with severe infections, and indicate that continuous infusion may be the best approach in terms of maximizing efficacy with time-dependent antimicrobials.

Determination of optimal dosage in the target animals is increasingly being recognized as vital for maximizing efficacy and minimizing the risk of resistance, so this study aimed to evaluate the pharmacokinetics/pharmacodynamics (PK/PD) of levofloxacin in broilers.