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The goal is to replace today's one-size-fits-all therapies with personalized treatment, maximizing efficacy and minimizing side effects.
To study the effect of different tumor subpopulations on treatment efficacy, Zhao et al. developed a multi-objective linear optimization algorithm to select optimal drug combinations for heterogeneous tumors by maximizing efficacy and minimizing toxicity [77].
Determination of optimal dosage in the target animals is increasingly being recognized as vital for maximizing efficacy and minimizing the risk of resistance, so this study aimed to evaluate the pharmacokinetics/pharmacodynamics (PK/PD) of levofloxacin in broilers.
Such patient stratification holds the potential for maximizing efficacy and minimizing toxicity.
Optimum formulation of adjuvant and vaccine is critical for maximizing efficacy and ease of use.
Pharmacologically, this is an attempt to remain on the steep portion of the "on-target" pharmacodynamic dose-response curve of two active agents of different therapeutic classes, thereby maximizing efficacy and minimizing bothersome dose sensitive "off-target" side effects.
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In order to maximize efficacy and minimize toxicity, new drugs have been developed and used in combination with CCRT.
In this commentary, we suggest a set of parameters to create culturally sensitive CBT in global settings in a way to maximize efficacy and effectiveness.
The protocol is designed to maximize efficacy and cultural congruency, adhering to the integrity of the holism, while addressing challenges arising from randomized controlled trial methods.
The use of genotype information in clinical psychopharmacology could potentially help clinicians avoid the standard trial and error approach, and allow a more efficient way to maximize efficacy and minimize toxicity [1] [3] as is done in certain situations with cancer treatment [4].
In practice, AEDs are titrated for each patient to maximize efficacy and tolerability of the drug.
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maximizing efficiency and
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maximize efficacy and
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optimizing efficacy and
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maximizing output and
maximizing camouflage and
maximizing durability and
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maximizing robustness and
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com