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The existing clinical trial model does not allow for modification of chemotherapeutic doses in a manner that maximizes the effect of biologic response modifiers and does not account for its "chemosensitizing" effect.
The amount of violations typically increases with the synthesis temperature, which maximizes the effect of the entropy contribution to the Gibbs free energy, and with the cooling rate, which should be fast enough to limit local atomic rearrangements in the favor of Si O Al bonds.
This allows transfer of the patient to a perinatal centre, and maximizes the effect of corticosteroids for improved neonatal survival.
Even including all inter-atomic distances in the calculation (Ro = ∞), which maximizes the effect of domain movement, does not significantly lower the correlation with domain-based GDC-all scores (R2 = 0.82).
Another, more efficient position (i.e. it maximizes the effect of drafting), is to offset your front wheel from the leader's rear wheel by a few inches, but trail within 1 foot (0.3 m).
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This may be attributed to the complicated design of the flow path close to the membrane surface which maximizes the effects of flow momentum on the oxygen flux.
The staircase was designed to maximize the effect of height.
The law has, in fact, been tweaked in ways that seem designed to maximize the effect of the Hobby Lobby decision.
To maximize the effect of the impact, the daughter spacecraft contained 360 kg (794 pounds) of solid copper.
"Although the word 'pound' has a connotation that can be misleading," Dr. Hogan said, "the idea is to train the brain to minimize time on the ground and maximize the effect of that time on the ground".
"If an author tells a publisher, 'I'm giving you a week' or 'I'm giving you two weeks,' what you need to do is maximize the effect of that time".
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