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RESULTS: Receiver-operator characteristic curve analyses showed that no 1 combination of severity and frequency criteria maximized sensitivity and specificity.
Indeed, 4 out of the 20 pairwise comparisons between recording sessions with different angles resulted in a DI <1.67%, i.e. the optimal threshold that maximized sensitivity and specificity (repeatability) of TMS-evoked potentials in the ROC analysis.
Cutoffs for classification models were selected to maximized sensitivity and specificity.
However, ideal systems with maximized sensitivity and data reproducibility have not been achieved.
ROC analysis was used to determine optimal cutoff points with combined maximized sensitivity and specificity (by Youden index).
Trevisani et al. defined an alpha-fetoprotein level of 16 ng/ml as the threshold that maximized sensitivity and specificity for the diagnosis of HCC [ 16].
Similar(41)
A total of 237 pairs of ELISA and RT-qPCR results from red deer were used for receiver operating characteristic analysis, which yielded an area under the curve of 0.811 and a cutoff value for the ELISA that maximized sensitivity (86%) and specificity (98%).
Then the optimal thresholds for A1C and fasting glucose that maximized sensitivity + specificity were identified, and corresponding sensitivity and specificity were presented.
The advantages of the device are the use of minimal liquid and maximized sensitivity for measuring viscosity.
We selected the optimum CES-D cutoff scores that concurrently maximized sensitivity (Se), specificity (Sp) and positive predictive values (PPV) when compared to the psychiatrist administered MINI-D assessment.
An alternate approach that used separate threshold values maximized sensitivity (threshold value ≥15.8 mm/mm, sensitivity 91%, negative likelihood ratio 0.16) and specificity (≤11.5 mm/mm, specificity 93%, positive likelihood ratio 8.5).
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