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Codon bias is thought to maximize translation efficiency, including speed and/or fidelity.
Frequent use of 'preferred codons' is believed to maximize translation efficiency.
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Finally, to show one potential application of our model, we used our model to design alterations in the translation-initiation region of the DsRed2 gene, and showed that these alterations could be used to maximize translational efficiency and transform a low-expressing DsRed2 gene into a high-expressing gene.
Since the attachment cells were never exposed to cold shock before they were mixed with RNAlater, we believe the up-regulation of cold-shock protein genes in M. aeruginosavorus serves to maximize the translation efficiency [ 58].
We have also modified antigen, repressor and plasmid vector sequences to enhance transcription and translation efficiencies to maximize protective antigen synthesis in vivo.
However, dynamic changes in mRNA folding throughout translation make it difficult to assess translation efficiency.
Instead we see increased translation efficiency.
Priming signal was normalized to translation efficiency.
The translation efficiency was monitored by eGFP fluorescence.
We identified ~550 genes exhibiting differential translation efficiency (TE).
The 5' UTR sequences may affect translation efficiency [ 17, 18].
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