F3 larvae were reared at a low density (approximately 125 per tray) to maximize their survival.
These progenitor cells were sorted into ice-old culture alpha MEM supplemented with 20% FBS to maximize their survival rate.
It is proposed that L. monocytogenesis uses this mechanism to manipulate the host cell to maximize their survival and proliferation.
Thus, it is likely that strains have acquired and/or adapted specific effectors, or encoding functions, to mediate distinct strategies that maximize their survival, replication and dissemination potential in their host.
Ultimately, we believe that the results reported in this study will accelerate the development of a personalized treatment for metastatic OS patients to maximize their survival and decrease treatment toxicity.
To maximize their survival and reproduction, bacteria have indeed developed numerous competition strategies, including interference competition where a species directly harms another via active production of toxin and other effectors [ 4, 6- 8].
