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The formulation optimization was performed using three factor two level full factorial design so as to minimize the particle size and zeta potential, maximize the entrapment efficiency as well as maximize the concentration of drug in brain with maximized brain/plasma ratio of the drug.
This facilitates replenishment of gases to the membrane surface to maximize the concentration gradients spanning fiber walls.
This matrix was previously selected to maximize the concentration of extracted all-trans lycopene among other matrices [10].
The design functions are optimized to maximize the concentration of C11+ at the end of reactor path.
The influence of different reaction variables has been evaluated in order to identify optimal process conditions and to maximize the concentration of peroxide produced in the liquid phase.
Equations and diagrams are presented that show the importance of different parameters to maximize the concentration of an intermediate in a plug-flow reactor.
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Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor.
When applied in this novel approach, the H2S passing through the membrane dissolves into a receiving solution containing a chemical, e.g. amines or sodium hydroxide, which immediately converts the H2S to a non-hazardous form thereby maximizing the concentration gradient across the membrane.
During CRRT the addition of countercurrent dialysate flow accomplishes diffusive clearance by maximizing the concentration gradient between blood and dialysate through the length of the membrane.
We believe that maximizing the concentration of antibiotics at the likely sites of infections, namely the interstitial fluid, will help to obviate the problem of inadequate prophylaxis.
In a low pH environment, the abundant protons saturate metal binding sites in the solution, maximizing the concentration of soluble metal ions.
More suggestions(15)
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maximize the ability
maximize the achievement
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