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Examining the validity of BR rate as a BD endophenotype however requires large-scale datasets (n = 1000 s to 10,000 s), a standardized testing protocol, and optimization of stimulus parameters to maximize separation between BD and healthy groups.
In CDA, Y1,Y2 and X1,X2 are chosen so as to maximize separation between the clusters.
We used the allometry-adjusted Procrustes coordinates as input data for canonical variates analysis (CVA), a discriminant analysis used to explore shape variation and to maximize separation between the four pre-defined groups of newborn mice, including: Fgfr2 +/S252W and Fgfr2 +/P253R Apert syndrome mice and their respective unaffected littermates.
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Golf instructors can consider increasing ball velocity by maximizing separation between the upper torso and pelvis at the top of and initiation of the downswing.
To test if incorporation of class labels information improves separation of cytokine treatments we used PLS Discriminant Analysis (PLS-DA), which maximizes separation between groups of observation/response variables by rotating PCA components such that the maximum separation among different classes is obtained.
The test provides maximal separation between the groups (see Everitt, 2005) in the form of a linear function of the observed variables such that the ratio of the between-groups variance to its within-group variance is maximized.
MSP transforms the feature space of data to maximize the separation between target and background signals.
The proposed method weighs each feature in terms of its capability to maximize the separation between class means.
LDA uses class information to maximize the separation between various groups of observations.
PLS-DA uses group information to maximize the separation between groups of observations.
The goal of any method is to score genes in such a way as to maximize the separation between native genes and genes of foreign origin.
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CEO of Professional Science Editing for Scientists @ prosciediting.com