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We decided to search for eligible articles including images by searching all the articles of a specific year one-by-one by hand, so as to maximize sensitivity for finding the eligible articles.
In both the elevated plus maze and the light-dark exploration test, light levels were very low (see methods for details) in an attempt to maximize sensitivity for detecting potential anxiogenic effects of mGluR5 haploinsufficiency (we hypothesized that anxiety-related phenotypes may track with the OSS data).
For all analytes, the ICP MS was run in collision-reaction cell mode with pure H2 as the cell gas to maximize sensitivity for Se determination.
We chose this approach to maximize sensitivity for estimating the relative impact of a lifestyle intervention on changes in all three risk factors combined, not to provide absolute risk estimates.
Please note that our use of an occipital surface coil, in order to maximize sensitivity for visual cortex, inevitably meant that we could not record attention-related and/or TMS-related signals in more anterior structures, such as frontal cortex.
Our approach to analysis of microarray data is to try to maximize sensitivity for detection of differences between experimental groups, and accuracy of estimation of absolute methylation fraction is, if anything, secondary.
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When maximizing sensitivity for detecting cost studies, the single term "exp economic aspect" produced the highest sensitivity at 98.9% with a specificity of 93.1%.
From consensus criteria (Litvan et al., 1996 a, d, 2003) we derived simplified operational diagnostic criteria suitable for large-scale clinical trials, with the aim of maximizing sensitivity for recruitment.
It was reported that scores ≥16 maximize sensitivity and specificity for depressive symptoms in patients with ESRD [ 16, 17].
This combination of the depth of exonic sequencing provided by exon capture with the breadth of coverage of WGS on a different sequencing platform, alongside the use of multiple variant-calling pipelines, provides a powerful means to maximize sensitivity and specificity for any one personal genome.
We optimized an algorithm to maximize sensitivity and positive predictive value for type 1 diabetes by combining all the high positive predictive value candidate algorithms using "or" statements (Table 4).
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