Sentence examples for maximize gene delivery from inspiring English sources

These parameters must be optimized for each tissue in order to maximize gene delivery while minimizing irreversible cell damage.

Although the results of these initial studies are promising, further studies to optimize viral vectors, maximize gene delivery, minimize side-effects, and develop cell-specific and long-term regulated gene expression are critical to the success of gene therapy targeted to specific compartments of the kidney.

Thus, matrix degradation and cell migration are fundamental design parameters for maximizing gene delivery within hydrogels.

Bypass grafting presents an ideal opportunity for gene therapy, as surgically harvested vein grafts can be treated with gene delivery vectors ex vivo, thereby maximizing gene delivery while minimizing the potential for systemic toxicity and targeting the pathogenesis of vein graft disease at its onset.

Optimizing the administration techniques to maximize gene distribution and gene expression is an important step in developing gene therapy studies.

Here, we performed analyses to maximize gene sampling.

In phylogenomics, EST studies can maximize taxonomic sampling, whereas studies using complete genomes can maximize gene sampling.

We pooled RNA from the two short exposures to maximize gene discovery.

We pooled RNA isolated from with 1.5- and 3-h As treatment to maximize gene discovery.

Combinations of library normalization and deep sequencing are used to maximize gene discovery.

Tightly controlled spatial localisation of therapeutic gene delivery is essential to maximize the benefits of somatic gene therapy in vivo and to reduce its undesired effects on the 'bystander' cell populations, most importantly germline cells.