Sentence examples for maximize efficacy in from inspiring English sources
We generated new pimelic diphenylamide HDACIs to maximize efficacy in upregulating frataxin and to optimize pharmacological properties in view of a future translation to the clinic.
This could potentially open up the way for redesigning the IL2 protocols to maximize efficacy in most patients.
Previous studies showed that knowledge and theoretical competences about the proper use of technical control measures (e.g., connecting hoses and removing bags correctly, good sealing, maintenance and cleaning) are needed to maximize efficacy in controlling exposure [ 28– 30].
Therefore, it is important to confirm tumour selectivity of a novel candidate mAb to minimize toxicity and maximize efficacy, preferably in early stages of drug development.
In order to maximize efficacy and minimize toxicity, new drugs have been developed and used in combination with CCRT.
The PK/PD index and target drug exposures obtained in validated animal infection models are critical components in optimizing dosing regimen design in order to maximize efficacy while minimize the cost and duration of clinical trials.
Such definitive reconstruction of phylogenetic trees is becoming increasingly important, particularly in the light of the failure of many targeted therapies to offer anything other than a minor overall survival benefit (37), which might relate to the requirement for targeting of driver mutations that are present in all the malignant cells in order to maximize efficacy (2).
In this commentary, we suggest a set of parameters to create culturally sensitive CBT in global settings in a way to maximize efficacy and effectiveness.
This model of personalized medicine integrates a patient's demographic and biological data (pharmacodynamic, genomic, epigenomic, transcriptomic, and metabolic information) to target therapy in order to maximize efficacy while minimizing bleeding and costs.
Sex should be considered when effective vaccine and antiviral dosages are determined in order to maximize efficacy while limiting adverse side effects.
The findings from this study suggest that an even more sophisticated method of optimization may be necessary in selected patients - patient-tailored antibiotic therapy - which is the adaptation of antibiotic therapy to the need of the individual patient in order to maximize efficacy and minimize toxicity through therapeutic drug monitoring and dose adaptation.
