Haplotypes and diplotypes were determined using the Partition-Ligation-Expectation-Maximization (PLEM) 1.0 software [ 11].
In a maximization problem, the LINGO software found a possible interval for optimum value of objective function ((Z^)) that is limited by the Z bound and Z best values, where Z best ≤ (Z^) ≤ Z bound.
Haplotypic frequencies were calculated from genotype data by expectation maximization (EM) algorithm using Arlequin software package version 3.0 (Laurent Excoffier, CMPG, Zoological Institute, University of Bern, Switzerland) [63].
Haplotypes of the LD block 3 defined two SNPs, rs6220 and rs7136446, were inferred using expectation-maximization algorithm in SNPAlyze software ver.7 (Dynacom Co. Ltd., Chiba, Japan).
Poly Refrigerant Integrated Cycle Operations PRICOO) process is simulated in HYSYS environment and linked to MATLAB software for subsequent maximization.
The Multiple expectation maximization for motif elicitation online software was used as a secondary method to analyze motif distribution and confirm the results of domain prediction.
Based on the genotype data of the genetic variations, linkage disequilibrium (LD) analyses and a haplotype-based case control study were carried out using the expectation maximization algorithm with the SNPAlyze software program ver3.2 (Dynacom, Yokohama, Japan).
Haplotype frequencies were estimated by the expectation-maximization algorithm using the tagSNP software.
The abundance of transcripts was then estimated using an Expectation-Maximization algorithm implemented in the software package RSEM [ 29] v1.1.13.
