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Furthermore, we wanted to maximise the sample size and hence the power in our calculations of, especially, the genetic correlation in lifetime fitness across the sexes.
We also used multiple imputation to maximise the sample size available.
To maximise the sample size in the analyses, unconditional logistic regression was also performed.
However, both of the above measures were incorporated into the study design to maximise the sample size.
20 The data sets used in this study were the 2003, 2008 and 2013 NDHS surveys, pooled together to maximise the sample sizes of deaths.
30 32 The serial cross-sectional analysis of four waves of ELSA included all eligible participants in each wave in order to maximise the sample size.
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Assuming an exposure prevalence of 50% maximises the sample size necessary to detect a relative risk of this magnitude.
Using a self-completion questionnaire for most of the data collection maximises the sample size for a given budget, whilst retaining the original sample design.
Switching to a self-completion mode for the bulk of data collection maximises the sample size for a given budget, whilst retaining the features of the original sample design.
7 years was the measurement occasion which maximised the sample size due to loss of stepfather households at older ages, with the biggest issue being non-response and drop-outs.
All of these considerations should be balanced against maximising the sample size to get a more reliable estimate of the treatment effect; examination of secondary end points (DeMets, 2006) and important, pre-specified subgroup analyses; and not missing an intervention with a moderate benefit, which is still clinically worthwhile.
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