AUY was maximally effective when applied to cells for 12 h but only marginally effective when applied to cells for 6 h.
The embedded Nb nanowires, with a volume fraction of 25%, were revealed capable of carrying at maximally 70% of the applied load at the completion of SIMT of NiTi matrix, and were capable of carrying more than 55% of the applied load at the terminal of deformation.
Thirty-two septic mechanically ventilated patients (mean ± SD, age 58 ± 14 years) were randomized to one of the two 30-min NMES protocols of different characteristics: a high-frequency (75 Hz, 6 s on 21 s off) or a medium-frequency (45 Hz, 5 s on 12 s off) protocol both applied at maximally tolerated intensity.
Then a 2-s conditioning pulse to −10 mV was applied to maximally inactivate Ito [12], so that a current trace without Ito was recorded during the step to +50 mV (dotted trace).
Single concentrations (0.1, 0.3, 1, 3, 10 μM) were applied to maximally activated Orai currents in individual cells, which was required due to the slow rate of reaching steady-state inhibition (Fig. 5).
In other words, the similarity rules will apply maximally to the members of one cluster and minimally to members belonging to the rest of the clusters.
To do this we produced membranes with a desired mole fraction of full-length PIP2 in the lipid mixture, recorded GIRK2 currents, and then applied C8-PIP2 to maximally activate (or nearly so), as shown.
Thus even under dynamic conditions, the loads applied by a maximally-active multifidus muscle to the facet capsular ligament are potentially large (43% on average) compared to the capsule's estimated sub-catastrophic failure loads.
The loads applied by a maximally-active multifidus muscle to the facet capsule are potentially a large proportion (about 64% on average) of the quasi-static loads (21 to 93 N; 45 ± 21 N) required to cause sub-catastrophic failures in the capsular ligament [ 7].
