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In healthy individuals, most activities require only a fraction of maximal working capacity, as assessed by maximal VO2 (VO2 Max).
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Submaximal constant work rate exercise time at 75% of the patient's maximal work capacity was the primary outcome.
Work was normalized to individual maximal work capacity (Wmax).
or relative to an individual's maximal work capacity (percentage of VO2max, etc).
Progressive cycle ergonometric testing was performed to maximal work capacity with test duration ranging from 6‐ 12 minutes.
The validation of the cycle ergometer test found a strong correlation between maximal work capacity and VO2max, and acceptable test-retest reliability at group level.
Lastly, our data indicate that exercising for 60 minutes at 50% of maximal work capacity does not significantly increase expression of circulating inflammatory cytokines.
Vollaard et al. [ 41] find these local changes in muscle metabolism are associated with changes in maximal work capacity more so than VO2max.
Maximal oxygen uptake (VO 2max) was measured using a maximal indirect cycle ergometer test modified from Pedersen & Nielsen [ 21], where VO2max was calculated from the maximal work capacity (Wmax).
Prior to the experiment, subjects were accustomed to exercise on the knee extension ergometer and maximal work capacity (Wmax) was determined for each leg as described by Andersen and Saltin (1985).
17 A previous trial of aerobic exercise in SBMA conducted with eight subjects did not show a benefit in the primary outcome measure of maximum oxygen uptake or in activities of daily living, however, a significant increase in maximal work capacity was observed.
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