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This application of the principle of the maximal difference was used already in the famous Shell 1973 scenarios.
A 400-m run at maximal speed was used as a functional measurement, which we have previously used successfully [2, 3].
The electrode site at which each ERP component reached its maximal amplitude was used in analyses.
The half maximal IC50 was used as a measure of the effectiveness of a drug on the cell lines.
From the recorded AUCs, the feature subset corresponding to the maximal AUC was used to train our final SVM model.
Maximal METs was used as dichotomous variables with a cut-off value of 7 which has been traditionally used and shown to be predictive of outcome.
Endogenous glucose production (EGP) and insulin mediated glucose disposal (IMGD) were calculated as before, 15 and the maximal IMGD was used for analyses.
The sub maximal protocol was used for the exercise test in which the subject would be over 85% of the maximum frequency.
Static polar maps were normalized to their maximum and a threshold of 60% of the individual maximal uptake was used to define the perfusion defect.
Peak speed and maximal treadmill speed was used to assess peak and maximal work rates in the VO2max and Vmax test.
However, instead of plateau pressure, maximal airway pressure was used since pressure-controlled ventilation was used exclusively in our setting.
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